Article
Behavioural characterization and amounts of brain monoamines and their metabolites in mice lacking histamine H1 receptors.
Neuroscience - 1 Nov 1998
Yanai K, Son L Z, Endou M, Sakurai E, Nakagawasai O, Tadano T, Kisara K, Inoue I, Watanabe T, Watanabe T
Abstract excerpt
Behavioural assessments were made of mutant mice lacking histamine H1 receptors to reveal the function of H1 receptors in the behaviour of mice. Exploratory behaviour of mice in a new environment was examined to discover whether the absence of H1 receptors in mice affects actions relating to their emotions. The H1 receptor-deficient mice showed a significant decrease in ambulation in an open field and on an...
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