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Article

Sustained somatic gene inactivation by viral transfer of Cre recombinase.

Nature biotechnology - 1 Nov 1996

Rohlmann A, Gotthardt M, Willnow T E, Hammer R E, Herz J

Abstract excerpt

Transgenic and knockout mice have proven invaluable tools for analyzing physiologically relavant functions of numerous genes. In some cases, however, pleiotropic effects that result from a variable requirement for a particular gene in different tissues, cell types, or stages of embryonic development may complicate the analysis due to a complex phenotype or embryonic lethality. The loxP/Cre-mediated recombination...

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Identifiers

PMID: 9634821
DOI: 10.1038/nbt1196-1562

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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