Article
Ectodomains of the LDL receptor-related proteins LRP1b and LRP4 have anchorage independent functions in vivo.
PloS one - 7 Apr 2010
Dietrich Martin F, van der Weyden Louise, Prosser Haydn M, Bradley Allan, Herz Joachim, Adams David J
Abstract excerpt
BACKGROUND: The low-density lipoprotein (LDL) receptor gene family is a highly conserved group of membrane receptors with diverse functions in developmental processes, lipoprotein trafficking, and cell signaling. The low-density lipoprotein (LDL) receptor-related protein 1b (LRP1B) was reported to be deleted in several types of human malignancies, including non-small cell lung cancer. Our group has previously...
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