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Article

The proliferation-associated early response gene p22/PRG1 is a novel p53 target gene.

Oncogene - 14 May 1998

Schäfer H, Trauzold A, Sebens T, Deppert W, Fölsch U R, Schmidt W E

Abstract excerpt

The novel early response gene p22/PRG1 is linked to cell cycle entry and the induction of proliferation in various cell types although its exact function is still unknown. The p22/PRG1 promoter region contains a 20 bp sequence matching the consensus binding motif for the tumor suppressor protein p53. Gel shift assays demonstrated that p53 specifically binds to an oligonucleotide derived from the p53 binding site...

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PMID: 9627114
DOI: 10.1038/sj.onc.1201788

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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