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Article

Role of p53 mutations, protein function and DNA damage for the radiosensitivity of human tumour cells

1 Jan 2004

Abstract excerpt

PURPOSE: The tumour suppressor protein p53 is considered to have an impact on the radiosensitivity of tumour cells. However, this concept does not easily translate to the tumour sensitivity in the clinics. The aim of the present study was to determine whether a functional or dysfunctional p53 is associated with a sensitive or resistant phenotype. It was further studied whether DNA damage might be an additive...

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PMID: 14761850
DOI: 10.1080/09553000310001642902

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Source receipt: pubmed, retrieved 7 Sept 2026.

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