A high yield of translocations parallels the high yield of sister chromatid exchanges in the CHO mutant EM9.

doi:10.1016/s0027-5107(97)00241-8

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Article

A high yield of translocations parallels the high yield of sister chromatid exchanges in the CHO mutant EM9.

Mutation research - 26 Feb 1998

Domínguez I, Daza P, Natarajan A T, Cortés F

Abstract excerpt

The fluorescence plus Giemsa (FPG) and fluorescence in situ hybridization (FISH) techniques have been used to determine, respectively, the frequencies of sister chromatid exchanges (SCEs) and stable chromosome aberrations (translocations) induced by different concentrations of BrdU in the Chinese...

Topics

Animals
Bromodeoxyuridine
CHO Cells
Cricetinae
In Situ Hybridization, Fluorescence
Mutagens
Mutation
Sister Chromatid Exchange
Translocation, Genetic

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