Article
Enhanced stimulation of chromosomal translocations by radiomimetic DNA damaging agents and camptothecin in Saccharomyces cerevisiae rad9 checkpoint mutants.
Mutation research - 22 Mar 2004
Fasullo Michael, Zeng Li, Giallanza Peter
Abstract excerpt
Saccharomyces cerevisiae rad9 checkpoint mutants exhibit pleiotropic phenotypes, including higher frequencies of chromosome loss, radiation sensitivity, and decreased induction of DNA damage-inducible genes. We had previously shown that rad9 mutants exhibit higher frequencies of DNA damage-associated translocations but lower frequencies of DNA damage-associated sister chromatid exchange (SCE), compared to wild...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
