No evidence for involvement of the interleukin-10 -592 promoter polymorphism in genetic susceptibility to primary biliary cirrhosis.

doi:10.1016/s0168-8278(98)80232-8

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Article

No evidence for involvement of the interleukin-10 -592 promoter polymorphism in genetic susceptibility to primary biliary cirrhosis.

Journal of hepatology - 1 May 1998

Zappala F, Grove J, Watt F E, Daly A K, Day C P, Bassendine M F, Jones D E

Abstract excerpt

BACKGROUND/AIMS: Primary biliary cirrhosis is a chronic cholestatic liver disease with an autoimmune aetiology. Family studies, which have shown a significantly increased incidence of primary biliary cirrhosis in the close relatives of patients, suggest that genetic factors play a significant rol...

Topics

Autoimmune Diseases
Genes, MHC Class II
Genetic Carrier Screening
Genetic Predisposition to Disease
Genotype
HLA-DR Antigens
HLA-DR Serological Subtypes
Homozygote
Humans
Interleukin-10
Liver Cirrhosis, Biliary
Middle Aged
Polymerase Chain Reaction
Polymorphism, Genetic
Promoter Regions, Genetic
Reference Values

Source

Open in PubMed

Identifiers

PMID: 9625317
DOI: 10.1016/s0168-8278(98)80232-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9625317-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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