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Article

Tumour necrosis factor-alpha promoter polymorphisms in primary biliary cirrhosis.

Journal of hepatology - 1 Feb 1999

Jones D E, Watt F E, Grove J, Newton J L, Daly A K, Gregory W L, Day C P, James O F, Bassendine M F

Abstract excerpt

BACKGROUND/AIMS: The incidence of primary biliary cirrhosis (PBC) is increased in the close relatives of patients, suggesting that genetic factors play a role in disease susceptibility. Decreased in vitro production of tumour necrosis factor (TNF)-alpha has been reported in PBC patients, suggesting a potential aetiological role for this cytokine. The aim of this study was to examine two biallelic polymorphisms in...

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Source

Identifiers

PMID: 10068101
DOI: 10.1016/s0168-8278(99)80067-1

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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