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Article

Apolipoprotein E epsilon 4 allele and whole brain atrophy in late-onset Alzheimer's disease.

The American journal of psychiatry - 1 Jun 1998

Yasuda M, Mori E, Kitagaki H, Yamashita H, Hirono N, Shimada K, Maeda K, Tanaka C

Abstract excerpt

OBJECTIVE: Diffuse brain atrophy is one of the gross pathological features of Alzheimer's disease and is a result of degenerative changes. The epsilon 4 allele of apolipoprotein E (APOE) is a risk factor or susceptibility gene in late-onset sporadic Alzheimer's disease and may influence the pathological changes associated with the disease. The aim of this study was to examine the relationship between the APOE...

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Source

Identifiers

PMID: 9619150
DOI: 10.1176/ajp.155.6.779

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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