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SPECT and MRI analysis in Alzheimer's disease: relation to apolipoprotein E epsilon 4 allele.

Journal of neurology, neurosurgery, and psychiatry - 1 Jun 1996

Lehtovirta M, Soininen H, Laakso M P, Partanen K, Helisalmi S, Mannermaa A, Ryynänen M, Kuikka J, Hartikainen P, Riekkinen P J

Abstract excerpt

OBJECTIVES: The epsilon 4 allele of apolipoprotein E (ApoE) is a risk factor for late onset Alzheimer's disease. ApoE is present in senile plaques, neurofibrillary tangles, and cerebrovascular amyloid, and it is implicated in synaptogenesis. The effect of ApoE polymorphism on the volumes of hippo...

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Alleles
Genotype
Aged
Gene Expression
Apolipoproteins E
Alzheimer Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Magnetic Resonance Imaging

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PMID: 8648331
DOI: 10.1136/jnnp.60.6.644
PMCID: PMC1073948

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026. Prepared record publication-8648331-2026-08-31.1. Manifest publication-graph-cohort-2026-08-31.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 31 Aug 2026.

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