Article
Allele-specific loss of heterozygosity in multiple colorectal adenomas: toward an integrated molecular cytogenetic map II.
Cancer genetics and cytogenetics - 1 May 2006
Mao Xin, Hamoudi Rifat A, Talbot Ian C, Baudis Michael
Abstract excerpt
Colorectal cancer (CRC) remains a significant public health challenge despite our increased understanding of the genetic defects underlying the pathogenesis of this common disease. It has been thought that multiple mechanisms lead to the malignant phenotype, with familial predisposition syndromes accounting for only a small proportion of all CRC cases. To identify additional loci likely involved in CRC and to...
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