Article
Allele loss, replication errors and loss of expression of E-cadherin in colorectal cancers.
Gut - 1 May 1997
Ilyas M, Tomlinson I P, Hanby A, Talbot I C, Bodmer W F
Abstract excerpt
BACKGROUND: Loss of E-cadherin expression has been implicated in the development of invasive characteristics in colorectal carcinomas. Failure to express E-cadherin may result from mutations of the E-cadherin gene (HSECAD). AIMS: To examine the correlation between E-cadherin expression and genetic changes at HSECAD; and to examine differences in E-cadherin expression and genetic changes at HSECAD between three...
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