Article
Different genetic features associated with colon and rectal carcinogenesis.
Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Jun 2004
Frattini Milo, Balestra Debora, Suardi Simona, Oggionni Maria, Alberici Paola, Radice Paolo, Costa Aurora, Daidone Maria Grazia, Leo Ermanno, Pilotti Silvana, Bertario Lucio, Pierotti Marco A
Abstract excerpt
PURPOSE: The issue of whether colon and rectal cancer should be considered as a single entity or two distinct entities is still debated, and there is a need to improve studies addressing the heterogeneity of the pathogenetic pathway leading to sporadic colorectal cancers (SCRCs) as well as to identify biological and/or molecular differences between colon and rectal cancers. EXPERIMENTAL DESIGN: Specimens of SCRCs...
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