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Article

Variability of persisting MHV RNA sequences constituting immune and replication-relevant domains.

Virology - 10 May 1998

Bergmann C, Dimacali E, Stohl S, Wei W, Lai M M, Tahara S, Marten N

Abstract excerpt

Survivors of acute infection with the neurotropic JHM strain of mouse hepatitis virus develop a persistent infection of the central nervous system associated with chronic ongoing demyelination. Persistence is characterized by viral RNA in the absence of infectious virus. To associate persistence with possible immune evasion and/or replication defects, viral RNA from brains of acutely and persistently infected...

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Identifiers

PMID: 9601524
DOI: 10.1006/viro.1998.9147

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