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Article

Analysis of the leader and capsid coding regions of persistent and neurovirulent strains of Theiler's virus.

Virology - 20 Dec 1995

Michiels T, Jarousse N, Brahic M

Abstract excerpt

Most strains of Theiler's virus (TMEV) cause a persistent infection of the central nervous system of the mouse and a chronic demyelinating disease considered a model for multiple sclerosis. Two strains, on the contrary, cause an acute encephalitis and kill mice in a matter of days. We sequenced the leader and capsid coding region of three persistent (TO4, WW, and Yale) isolates and one neurovirulent (FA) isolate...

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Identifiers

PMID: 8553557
DOI: 10.1006/viro.1995.0066

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