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Article

Enhancing leptin response by preventing SH2-containing phosphatase 2 interaction with Ob receptor.

Proceedings of the National Academy of Sciences of the United States of America - 26 May 1998

Carpenter L R, Farruggella T J, Symes A, Karow M L, Yancopoulos G D, Stahl N

Abstract excerpt

Leptin is an adipocyte-derived cytokine that regulates food intake and body weight via interaction with its Ob receptor (ObR). Serum leptin levels are chronically elevated in obese humans, suggesting that obesity may be associated with leptin resistance and the inability to generate an adequate O...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 9600917
DOI: 10.1073/pnas.95.11.6061
PMCID: PMC27585

Genes

STAT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-9600917-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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