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Article

A complex interaction pattern of CIS and SOCS2 with the leptin receptor

10 May 2006

Abstract excerpt

Hypothalamic leptin receptor signalling plays a central role in weight regulation by controlling fat storage and energy expenditure. In addition, leptin also has direct effects on peripheral cell types involved in regulation of diverse body functions including immune response, bone formation and reproduction. Previous studies have demonstrated the important role of SOCS3 (suppressor of cytokine signalling 3) in...

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Share to Adipokines, Inflammation, and Metabolic Diseases
Share to Cytokine Signaling Pathways and Interactions
Share to Regulation of Appetite and Obesity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16684815
DOI: 10.1242/jcs.02947

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