Article
Novel mutations in the polyadenine tract of the transforming growth factor beta type II receptor gene are found in a subpopulation of human pancreatic adenocarcinomas.
Genes, chromosomes & cancer - 1 Jun 1998
Venkatasubbarao K, Ahmed M M, Swiderski C, Harp C, Lee E Y, McGrath P, Mohiuddin M, Strodel W, Freeman J W
Abstract excerpt
In this study, we determined the incidence of microsatellite instability (MIN) in pancreatic adenocarcinoma and determined whether MIN might target, for mutations, the simple nucleotide repeats of the transforming growth factor beta type II receptor (TGFBR2) gene. Forty-eight surgically resected pancreatic tumor tissue samples and two normal pancreas tissue samples were analyzed in this study. Microsatellite...
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