Article
Regional reproducibility of microsatellite instability in sporadic colorectal cancer.
Genes, chromosomes & cancer - 1 Oct 1999
Samowitz W S, Slattery M L
Abstract excerpt
The reproducibility of microsatellite instability from different regions of the same sporadic colon cancer has not been addressed. We therefore microdissected and extracted DNA from three to nine separate regions of 13 highly unstable sporadic colon cancers. Each region was then evaluated by polymerase chain reaction amplification of 17 microsatellites: 10 tetranucleotide repeats, 2 noncoding mononucleotide...
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