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Article

Hypermutability at a poly(A/T) tract in the human germline.

Nucleic acids research - 1 Nov 2001

Bacon A L, Dunlop M G, Farrington S M

Abstract excerpt

Poly(A/T) tracts are abundant simple sequence repeats (SSRs) within the human genome. They constitute part of the coding sequence of a variety of genes, encoding polylysine stretches that are important for protein function. Assessment of poly(A/T) tract stability is also used to identify microsatellite unstable colorectal cancers, which are characteristic of tumours defective in DNA mismatch repair. Despite their...

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Identifiers

PMID: 11691928
DOI: 10.1093/nar/29.21.4405
PMCID: PMC60178

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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