Article
Microsatellite instability and K-ras mutations associated with pancreatic adenocarcinoma and pancreatitis.
Cancer research - 1 Oct 1995
Brentnall T A, Chen R, Lee J G, Kimmey M B, Bronner M P, Haggitt R C, Kowdley K V, Hecker L M, Byrd D R
Abstract excerpt
ras oncogene mutations and microsatellite instability (MIN) have been described in pancreatic cancer studies from paraffin blocks and fresh frozen tissue. We sought to determine whether they could be detected in endoscopic retrograde cholangiopancreatography-derived pancreatic juice. ras mutations were detected in the pancreatic juice of 40% (2 of 5) of patients with pancreatic cancer and 2 of 5 patients with...
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