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Article

Stepwise deletions of polyA sequences in mismatch repair-deficient colorectal cancers.

The American journal of pathology - 1 May 2001

Blake C, Tsao J L, Wu A, Shibata D

Abstract excerpt

PolyA simple repeat sequence deletions are common in tumors with microsatellite instability (MSI+). Such deletions occur one base at a time in DNA mismatch repair (MMR)-deficient yeast suggesting larger deletions in human MSI+ tumors represent multiple sequential stepwise losses. Sum total deleti...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 11337385
DOI: 10.1016/S0002-9440(10)64143-0
PMCID: PMC1891934

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11337385-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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