Article
Microsatellite instability and allelic losses in neuroendocrine tumors of the gastro-entero-pancreatic system.
International journal of oncology - 1 Aug 1999
Ghimenti C, Lonobile A, Campani D, Bevilacqua G, Caligo M A
Abstract excerpt
Carcinoids are well differentiated tumors, able to secrete a variety of bioactive and hormonal products. Neuroendocrine tumors occur either sporadically or as part of familial syndromes (MEN1, MEN2). Defective DNA mismatch repair is implicated in a variety of gastrointestinal and other cancers; however, its role in the tumorigenesis of carcinoids has not been assessed. Formalin-fixed, paraffin-embedded archivial...
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