Article
Most of CD30+ anaplastic large cell lymphoma of B cell type show a somatic mutation in the IgH V region genes.
Leukemia - 1 May 1998
Kuze T, Nakamura N, Hashimoto Y, Abe M
Abstract excerpt
Relationship and histogenesis of Hodgkin's disease (HD) and anaplastic large cell lymphoma (ALCL) still remain unclear. Recently, Reed-Sternberg cells or Hodgkin cells in HD with B cell phenotype (B-HD) are considered to originate from germinal center B cells, ALCLs of B cell phenotype (B-ALCL) are involved in diffuse large B cell lymphoma (DLBCL) as anaplastic variant, but an origin of tumor cells of B-ALCL has...
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