Most of CD30+ anaplastic large cell lymphoma of B cell type show a somatic mutation in the IgH V region genes.

doi:10.1038/sj.leu.2400998

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Article

Most of CD30+ anaplastic large cell lymphoma of B cell type show a somatic mutation in the IgH V region genes.

Leukemia - 1 May 1998

Kuze T, Nakamura N, Hashimoto Y, Abe M

Abstract excerpt

Relationship and histogenesis of Hodgkin's disease (HD) and anaplastic large cell lymphoma (ALCL) still remain unclear. Recently, Reed-Sternberg cells or Hodgkin cells in HD with B cell phenotype (B-HD) are considered to originate from germinal center B cells, ALCLs of B cell phenotype (B-ALCL) a...

Topics

Adult
Aged
Aged, 80 and over
Base Sequence
DNA, Neoplasm
Female
Gene Rearrangement, B-Lymphocyte
Genes, Immunoglobulin
Humans
Immunoglobulin Heavy Chains
Immunoglobulin Variable Region
Immunologic Memory
Ki-1 Antigen
Lymphoma, B-Cell
Lymphoma, Large-Cell, Anaplastic
Male
Middle Aged
Molecular Sequence Data

Source

Open in PubMed

Identifiers

PMID: 9593274
DOI: 10.1038/sj.leu.2400998

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9593274-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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