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Article

Molecular analysis of immunoglobulin genes in diffuse large B-cell lymphomas

1 Mar 2000

Abstract excerpt

Diffuse large B-cell lymphoma (DLBCL) is a common type of non-Hodgkin's lymphoma (NHL) that is highly heterogeneous from both clinical and histopathologic viewpoints. The immunoglobulin (Ig) heavy (H) chain variable region genes were examined in 71 patients with untreated primary DLBCL. Fifty-eight potentially functional V(H) genes were detected in 53 DLBCL cases; V(H) genes were nonfunctional in 9 cases and were...

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PMID: 10688840
DOI: 10.1182/blood.v95.5.1797.005k30_1797_1803

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