Article
Primary central nervous system lymphomas express Vh genes with intermediate to high somatic mutations.
Leukemia & lymphoma - 1 Apr 2001
Sekita T, Tamaru J I, Kaito K, Katayama T, Kobayashi M, Mikata A
Abstract excerpt
Primary central nervous system lymphoma (PCNSL) is a rare disease, especially among non-AIDS patients. Although almost all PCNSLs belong to the diffuse large B-cell lymphoma (DLBL) category, its clinical course differs from that of other types of DLBL. To elucidate the histogenesis of PCNSL, we analyzed the source of the cells from its variable region (VH) sequences using the polymerase chain reaction (PCR)...
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