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Article

[Effect of gene polymorphism on detoxifying glutathione-S-transferase enzymes on chromosomal stability of squamous epithelial carcinomas in the area of the head-neck].

Laryngo- rhino- otologie - 1 Apr 1998

Matthias C, Bockmühl U, Jahnke V, Petersen I, Dietel M, Fryer A, Strange R C

Abstract excerpt

BACKGROUND: While cigarette smoking and chronic alcohol consumption are the major risk factors for the development of head and neck cancer, it is assumed that genetic factors contribute to risk. MATERIAL AND METHODS: We examined genotype frequencies from leukocyte DNA of 269 laryngeal cancer patients, 123 pharyngeal cancer patients and 216 controls. Polymorphisms at different glutathione-S-transferase (GST) gene...

Read the complete abstract on PubMed

Topics

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Share to Carcinoma, Squamous Cell
Share to Chromosome Aberrations

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

Share to Gene Frequency

Share to Genotype

Share to Polymerase Chain Reaction

Share to Polymorphism, Genetic

Share to Risk Factors

Source

Identifiers

PMID: 9592753
DOI: 10.1055/s-2007-996961

Genes

GSTM1
GSTM3
GSTP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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