Article
[Immunohistologic and molecular genetic studies of the effect of glutathione-S-transferases on the development of squamous epithelial carcinomas in the area of the head-neck].
Laryngo- rhino- otologie - 1 Apr 1999
Matthias C, Jahnke V, Hand P, Fryer A A, Strange R C
Abstract excerpt
BACKGROUND: While cigarette smoking and alcohol consumption are the major risk factors for the development of head and neck carcinomas, it is assumed that genetic factors contribute to risk. The aim of this study was to characterize the influence of the carcinogen metabolizing glutathione-S-transferases on susceptibility to head and neck carcinomas. PATIENTS AND METHODS: Polymorphisms at GSTM1, M3, T1 and P1 gene...
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