Article
[Influence of glutathione s-transferase and cytochrome p450 polymorphisms on prognosis of head and neck cancer].
Laryngo- rhino- otologie - 1 Jun 2002
Matthias C, Jahnke V, Fryer A A, Strange R C
Abstract excerpt
BACKGROUND: The polymorphic gene loci of the detoxifying enzymes GST and CYP are susceptibility factors for head and neck cancer. Recently, they have been associated with outcome in several cancers. METHODS: Accordingly, we have examined, in patients with squamous cell carcinoma (SCC) of the head and neck, associations between GSTM1, GSTT1, GSTM3, GSTP1, CYP2D6, CYP1A1 and CYP2E1 genotypes and outcome parameters,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
