Article
Allelic imbalance mapping of chromosome 16 shows two regions of common deletion in prostate adenocarcinoma.
Cancer genetics and cytogenetics - 1 Oct 1997
Godfrey T E, Cher M L, Chhabra V, Jensen R H
Abstract excerpt
Allelic imbalance (AI) has now been reported on the long arm of chromosome 16 in several cancers including breast, prostate, hepatocellular carcinoma, and Wilms tumor. Such nonrandom AI is commonly associated with the presence of a tumor suppressor gene (TSG) at or near the tested locus. Previous studies in our laboratory indicated that prostate cancer genomes frequently exhibit a region of allelic loss near the...
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