Article
Sublethal damage repair capacity in carcinoma cell lines with p53 mutations.
Head & neck - 1 Jul 1998
Pekkola-Heino K, Servomaa K, Kiuru A, Grenman R
Abstract excerpt
BACKGROUND: The previous findings that sublethal damage repair (SLDR) capacity varies between carcinoma cell lines and that the inherent radiosensitivity of these lines tends to be higher in connection with p53 mutations lead us to study the possible role of p53 gene in the regulation of SLDR. The activation of p53 gene by irradiation is known to cause changes in cell cycle progression. Thus, p53 status probably...
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