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Article

Evidence for the expression of radiation-induced potentially lethal damage being a p53-dependent process.

International journal of radiation biology - 1 Aug 2000

Schwartz J L, Jordan R, Kaufmann W K, Rasey J, Russell K J, Weichselbaum R R

Abstract excerpt

PURPOSE: To test the hypothesis that the expression of potentially lethal damage (PLD) is a p53-dependent process. MATERIALS AND METHODS: Previously reported data on radiation sensitivity, DNA double-strand break rejoining, PLD expression and repair (PLDR) were analyzed for a group of 12 human tumor cell lines and three human diploid fibroblast cell lines. Seven of these cell lines had normal p53 gene expression...

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Identifiers

PMID: 10947116
DOI: 10.1080/09553000050111505

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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