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Article

p53 mutation does not correlate with radiosensitivity in 24 head and neck cancer cell lines.

Cancer research - 15 Aug 1993

Brachman D G, Beckett M, Graves D, Haraf D, Vokes E, Weichselbaum R R

Abstract excerpt

The molecular basis of tumor response to therapeutic radiation is poorly understood. Recent evidence suggests the p53 tumor suppressor gene may be involved in production of the G1 arrest seen following DNA damage by X-irradiation. It has further been proposed that tumor cells lacking the p53 checkpoint function are likely to be more sensitive to cell killing by X-irradiation because these cells enter S phase...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 8339273

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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