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Correlation between cellular radiosensitivity and non-repaired double-strand breaks studied in nine mammalian cell lines

1 Jan 1998

Abstract excerpt

PURPOSE: To test the relationship between cell killing and non-repaired DNA strand breaks both in repair proficient and deficient cell lines. MATERIALS AND METHODS: Five of the cell lines used are repair competent (CHO, CHO K1, rat rhabdomyosarcoma R1H, mouse balb and normal human fibroblasts), while four display a reduced repair capacity (scid, xrs1, xrs5, AT). Cell survival was determined by colony formation...

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PMID: 9525255
DOI: 10.1080/095530098142365

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