Article
Histone- and Protamine-DNA Association: Conservation of Different Patterns within the β-Globin Domain in Human Sperm
1 Jun 1998
Abstract excerpt
Most DNA in human sperm is bound to highly basic proteins called protamines, but a small proportion is complexed with histones similar to those found in active chromatin. This raises the intriguing possibility that histones in sperm are marking sets of genes that will be preferentially activated during early development. We have examined the chromatin structure of members of the beta-globin gene family, which are...
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