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Article

Expression of protamine-1 and -2 mRNA during human spermiogenesis

1 Mar 2000

Abstract excerpt

During spermiogenesis, the histone-to-protamine replacement causes the compaction of the spermatid chromatin. The genes for protamines, PRM-1 and PRM-2, are transcribed in round and elongating spermatids. The transcripts are stored in a translationally-repressed state by the binding of protein repressors before being translated in elongating and elongated spermatids. RNA extracts from homogenized whole testis...

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Identifiers

PMID: 10694268
DOI: 10.1093/molehr/6.3.219

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