Article
Isolation of four core histones from human sperm chromatin representing a minor subset of somatic histones.
The Journal of biological chemistry - 25 Nov 1990
Gatewood J M, Cook G R, Balhorn R, Schmid C W, Bradbury E M
Abstract excerpt
Using high performance liquid chromatography we have successfully purified four core histones from mature human sperm chromatin. The H2A variants present in sperm (H2A.X and limited H2A.Z) have been shown previously to be minor variants in somatic chromatin. The histones are highly modified as evidenced by extensive acetylation and an as yet uncharacterized multicharge modification of H2B. Based on our data, we...
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