Isolation of four core histones from human sperm chromatin representing a minor subset of somatic histones.

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Article

Isolation of four core histones from human sperm chromatin representing a minor subset of somatic histones.

The Journal of biological chemistry - 25 Nov 1990

Gatewood J M, Cook G R, Balhorn R, Schmid C W, Bradbury E M

Abstract excerpt

Using high performance liquid chromatography we have successfully purified four core histones from mature human sperm chromatin. The H2A variants present in sperm (H2A.X and limited H2A.Z) have been shown previously to be minor variants in somatic chromatin. The histones are highly modified as ev...

Topics

Amino Acids
Chromatin
Chromatography, High Pressure Liquid
Electrophoresis, Gel, Two-Dimensional
Electrophoresis, Polyacrylamide Gel
Genetic Variation
Histones
Humans
Male
Molecular Weight
Spermatozoa

Source

Open in PubMed

Identifiers

PMID: 2243112

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2243112-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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