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Article

Protamine alterations in human spermatozoa.

Advances in experimental medicine and biology - 1 Jan 2014

Jodar Meritxell, Oliva Rafael

Abstract excerpt

Protamines are the major nuclear proteins in sperm cells, having a crucial role in the correct packaging of the paternal DNA. The fact that protamine haploinsufficiency in mice resulted in abnormal chromatin packaging and male infertility suggested that the protamines could also be important candidates in explaining some of the idiopathic male infertility cases in humans. The first clinical studies focused on...

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Identifiers

PMID: 23955674
DOI: 10.1007/978-1-4614-7783-9_6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Protamine alterations in human spermatozoa.PMID 23955674Read ↗

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Altered protamine expression and diminished spermatogenesis: what is the link?Semantic proximity Read ↗

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Single nucleotide polymorphisms in the protamine-1 and -2 genes of fertile and infertile human male populations.Semantic proximity Read ↗

Haploinsufficiency of protamine-1 or -2 causes infertility in mice.Semantic proximity Read ↗

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