Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Art of Packaging the Sperm Genome: Molecular and Structural Basis of the Histone-To-Protamine Exchange

22 Jun 2022

Abstract excerpt

Male fertility throughout life hinges on the successful production of motile sperm, a developmental process that involves three coordinated transitions: mitosis, meiosis, and spermiogenesis. Germ cells undergo both mitosis and meiosis to generate haploid round spermatids, in which histones bound to the male genome are replaced with small nuclear proteins known as protamines. During this transformation, the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animal Genetics and Reproduction
Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35813619
DOI: 10.3389/fendo.2022.895502

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Art of Packaging the Sperm Genome: Molecular and Structural Basis of the Histone-To-Protamine ExchangePMID 35813619Read ↗

Insights into the sperm chromatin and implications for male infertility from a protein perspectiveSemantic proximity Read ↗

Essential Role of Histone Replacement and Modifications in Male FertilitySemantic proximity Read ↗

A hidden protamine PTM code in sperm generates heterogeneous chromatin states and finetunes reproductive fitnessSemantic proximity Read ↗

Histone variants: essential actors in male genome programming.Semantic proximity Read ↗

Sperm chromatin condensation: epigenetic mechanisms to compact the genome and spatiotemporal regulation from inside and outside the nucleusSemantic proximity Read ↗

Human sperm chromatin epigenetic potential: genomics, proteomics, and male infertilitySemantic proximity Read ↗

Histone Variant H2A.L.2 Guides Transition Protein-Dependent Protamine Assembly in Male Germ Cells.Semantic proximity Read ↗

Sperm chromatin structure: Insights from in vitro to in situ experimentsSemantic proximity Read ↗

Sperm ChromatinSemantic proximity Read ↗

Paternal DNA packaging in spermatozoa: more than the sum of its parts? DNA, histones, protamines and epigeneticsSemantic proximity Read ↗

Function of sperm chromatin structural elements in fertilization and developmentSemantic proximity Read ↗

Exogenous Expression of Human Protamine 1 (hPrm1) Remodels Fibroblast Nuclei into Spermatid-like StructuresSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.