Article
Influence of tumour necrosis factor microsatellite polymorphisms on susceptibility to head and neck cancer.
Acta oto-laryngologica - 1 Mar 1998
Matthias C, Jahnke V, Fryer A, Strange R, Ollier W, Hajeer A
Abstract excerpt
While cigarette smoking and alcohol consumption are recognized covariates for head and neck squamous cell carcinoma (SCC), the role of genetic factors in determining individual susceptibility is unknown. The human tumour necrosis factor (TNF) region on chromosome 6p21 within the major histocompatibility complex (MHC) includes a number of immunologically important genes. Recently, five microsatellite markers have...
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