Article
Transforming growth factor-β1 gene polymorphism as a potential risk factor in Turkish patients with laryngeal squamous cell carcinoma.
Journal of cancer research and therapeutics - 1 Jan 2000
Abakay Candan Demiröz, Pashazadeh Mehrdad, Ardahanli Elif, Oral Haluk Barbaros
Abstract excerpt
INTRODUCTION: Laryngeal cancer is the most common head-and-neck malignancies with more than 20% of all cases. The vast majority of tumors are squamous cell carcinoma (SCC). Several genes encoding different cytokines may play crucial roles in host susceptibility to cancer because cytokine production capacity varies among individuals and depends on cytokine gene polymorphisms. MATERIALS AND METHODS: The association...
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