Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphism of Promoter Region of TNFRSF1A Gene (-610 T > G) as a Novel Predictive Factor for Radiotherapy Induced Oral Mucositis in HNC Patients.

Pathology oncology research : POR - 1 Jan 2018

Brzozowska Anna, Powrózek Tomasz, Homa-Mlak Iwona, Mlak Radosław, Ciesielka Marzanna, Gołębiowski Paweł, Małecka-Massalska Teresa

Abstract excerpt

Every year, about 650 thousand new cases of Head and Neck Cancer (HNC) are diagnosed globally. Apart from surgery, radiotherapy (RTH), chemotherapy (CHT) or its combination is used in the treatment of HNC. One of the most frequent complications and, at the same time, limitations of RTH is oral mucositis (OM). Proinflammatory cytokines (including TNF-α) play a key role in the development of OM. Genetic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to Follow-Up Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Head and Neck Neoplasms

Share to Polymorphism, Single Nucleotide

Share to Prognosis

Share to Promoter Regions, Genetic

Share to Radiotherapy

Share to Receptors, Tumor Necrosis Factor, Type I

Source

Open in PubMed Open full text

Identifiers

PMID: 28401452
DOI: 10.1007/s12253-017-0227-1
PMCID: PMC5736772

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphism of Promoter Region of TNFRSF1A Gene (-610 T > G) as a Novel Predictive Factor for Radiotherapy Induced Oral Mucositis in HNC Patients.PMID 28401452Read ↗

TNFRSF1A (-135 T>C, rs767455) Polymorphism as a Predictor of Radiation Induced Oral Mucositis and Treatment Response in Locally Advanced Head and Neck Cancer Patients.Semantic proximity Read ↗

Single-Nucleotide Polymorphisms and Cancer Risk, Tumor Recurrence, or Survival of Head and Neck Cancer Patients.Semantic proximity Read ↗

Protective role of TGF-β1 (-509C>T, rs1800469) single-nucleotide polymorphism against radiation toxicities in locally advanced head and neck cancer.Semantic proximity Read ↗

Risk genes in head and neck cancer: a systematic review and meta-analysis of last 5 years.Semantic proximity Read ↗

Potential Single Nucleotide Polymorphisms markers for radiation dermatitis in head and neck cancer patients: a meta-analysis.Semantic proximity Read ↗

Relationship between TNF-α -1031T/C gene polymorphism, plasma level of TNF-α, and risk of cachexia in head and neck cancer patients.Semantic proximity Read ↗

Predictive single nucleotide polymorphism markers for acute oral mucositis in patients with nasopharyngeal carcinoma treated with radiotherapySemantic proximity Read ↗

No association of TNF-α-308G/A polymorphisms with head and neck cancer risk: A PRISMA-compliant meta-analysis.Semantic proximity Read ↗

Association Between Head and Neck Cancers and Polymorphisms 869T/C, 509C/T, and 915G/C of the Transforming Growth Factor-β1 Gene: A Meta-Analysis of Case-Control Studies.Semantic proximity Read ↗

Association of hOGG1 Ser326Cys, ITGA2 C807T, TNF-A -308G>A and XPD Lys751Gln polymorphisms with the survival of Malaysian NPC patients.Semantic proximity Read ↗

Genetic polymorphism of tumor necrosis factor alpha (TNF-α) and tumor necrosis factor beta (TNF-β) genes and risk of oral pre-cancer and cancer in North Indian population.Semantic proximity Read ↗

TGFbeta1 genetic polymorphism is associated with survival in head and neck squamous cell carcinoma independent of the severity of chemoradiotherapy induced mucositis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.