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Article

[Influence of genetic variation in the major histocompatibility complex on head and neck cancer susceptibility].

Laryngo- rhino- otologie - 1 Oct 2001

Matthias C, Jahnke V, Hajeer A, Ollier W, Fryer A A, Strange R C

Abstract excerpt

BACKGROUND: While cigarette smoking and alcohol consumption are risk factors for squamous cell carcinomas (SCC) of the head and neck, genetic factors are also significant. The gene of tumor necrosis factor (TNF) is located in the major histocompatibility complex class III and the cytokine has pleiotropic actions some of which are anticarcinogenic. As this gene complex is polymorphic with microsatellite markers...

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Source

Identifiers

PMID: 11602932
DOI: 10.1055/s-2001-17837

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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