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Article

Association of common polymorphisms in TNFA, NFkB1 and NFKBIA with risk and prognosis of esophageal squamous cell carcinoma.

PloS one - 1 Jan 2013

Umar Meenakshi, Upadhyay Rohit, Kumar Shaleen, Ghoshal Uday Chand, Mittal Balraj

Abstract excerpt

BACKGROUND: Tumour necrosis factor-alpha (TNF-α) and nuclear factor of kappa light chain gene enhancer in activated B cells (NF-κB) play critical role in carcinogenesis processes like tumour initiation, proliferation, migration and invasion. Single nucleotide polymorphisms in TNF-α, NF-κB and its inhibitor IκB genes were shown to be associated with susceptibility and prognosis of several cancers; however, their...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24324738
DOI: 10.1371/journal.pone.0081999
PMCID: PMC3852749

Genes

NFKBIA
TNF

Provenance

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