Overexpression of manganese superoxide dismutase in DU145 human prostate carcinoma cells has multiple effects on cell phenotype.

doi:10.1002/(sici)1097-0045(19980515)35:3<221::aid-pros8>3.0.co;2-j

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Article

Overexpression of manganese superoxide dismutase in DU145 human prostate carcinoma cells has multiple effects on cell phenotype.

The Prostate - 15 May 1998

Li N, Oberley T D, Oberley L W, Zhong W

Abstract excerpt

BACKGROUND: Recent studies suggest that the gene for manganese superoxide dismutase (MnSOD) is a candidate tumor-suppressor gene. The present study was designed to study the effect of overexpression of MnSOD on cultured human prostate carcinoma cells. METHODS: DU145 human prostate carcinoma cells...

Topics

Animals
Antioxidants
Catalase
Clone Cells
Humans
Male
Mice
Mice, Nude
Mitochondria
Oxidation-Reduction
Phenotype
Prostatic Neoplasms
Reactive Oxygen Species
Superoxide Dismutase
Transfection
Tumor Cells, Cultured

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