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Article

Phenotypic changes induced in human breast cancer cells by overexpression of manganese-containing superoxide dismutase.

Oncogene - 18 May 1995

Li J J, Oberley L W, St Clair D K, Ridnour L A, Oberley T D

Abstract excerpt

Human manganese containing superoxide dismutase (MnSOD) cDNA was transfected into a human breast cancer cell line (MCF-7) in order to examine the effect of increased functional MnSOD on the cellular phenotype. A MnSOD-overexpressing clone was compared to control vector-transfected cells and to wild type MCF-7 cells. Southern blotting indicated incorporation of MnSOD cDNA into genomic DNA in the MnSOD...

Topics

Animals
Base Sequence
Breast Neoplasms
Cell Division
Female
Humans
Mice
Mice, Nude
Molecular Sequence Data
Phenotype
Pyruvates
Pyruvic Acid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

RNA, Messenger

Superoxide Dismutase

Transfection

Tumor Cells, Cultured

Source

Identifiers

PMID: 7761099

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7761099-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Phenotypic changes induced in human breast cancer cells by overexpression of manganese-containing superoxide dismutase.PMID 7761099Read ↗

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