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Manganese superoxide dismutase (MnSOD) genetic polymorphism is associated with risk of early-onset prostate cancer.

Cell biochemistry and function - 1 Oct 2008

Arsova-Sarafinovska Zorica, Matevska Nadica, Petrovski Daniel, Banev Saso, Dzikova Sonja, Georgiev Vladimir, Sikole Aleksandar, Sayal Ahmet, Aydin Ahmet, Suturkova Ljubica, Dimovski Aleksandar J

Abstract excerpt

Prostate cancer continues to be the most frequently diagnosed neoplasm, and the second leading cause of cancer-related mortality in men. Oxidative stress may enhance prostatic carcinogenesis. Manganese superoxide dismutase (MnSOD) is the only known superoxide scavenger in mitochondria. It plays a key role in antioxidant defense as mitochondria are important for oxidative metabolism coupled to the electron...

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PMID: 18646267
DOI: 10.1002/cbf.1504

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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