Article
Manganese-containing superoxide dismutase overexpression causes phenotypic reversion in SV40-transformed human lung fibroblasts.
Cancer research - 15 Jun 1996
Yan T, Oberley L W, Zhong W, St Clair D K
Abstract excerpt
Manganese superoxide dismutase (MnSOD) has been found to be low in a wide range of tumor cells as well as in vitro-transformed cell lines and has been implicated as a new type of tumor suppressor gene. The relationship between MnSOD activity and the malignant phenotype was studied by transfection...
Topics
- Cell Division
- Cell Line, Transformed
- Fibroblasts
- Genes, Tumor Suppressor
- Humans
- Lung
- Phenotype
- Simian virus 40
- Superoxide Dismutase
- Transfection