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Article

Manganese superoxide dismutase polymorphism, prediagnostic antioxidant status, and risk of clinical significant prostate cancer.

Cancer research - 15 Mar 2005

Li Haojie, Kantoff Philip W, Giovannucci Edward, Leitzmann Michael F, Gaziano J Michael, Stampfer Meir J, Ma Jing

Abstract excerpt

Oxidative stress may enhance prostatic carcinogenesis. A polymorphism [valine (V) --> alanine (A)] of manganese superoxide dismutase (MnSOD), the primary antioxidant enzyme in mitochondria, has been recently associated with prostate cancer. We examined the relationship between prostate cancer and the MnSOD polymorphism and its interactions with baseline plasma antioxidant levels (selenium, lycopene, and...

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Identifiers

PMID: 15781667
DOI: 10.1158/0008-5472.CAN-04-3535

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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